HEALTHY WORKING TIME ARRANGEMENTS FOR HEALTHCARE PERSONNEL AND PATIENTS: A SYSTEMATIC LITERATURE REVIEW


Efficacy of sofosbuvir as treatment for yellow fever: protocol for a randomised controlled trial in Brazil (SOFFA study)

Introduction An ongoing outbreak of yellow fever (YF) has been reported in Brazil with 1261 confirmed cases and 409 deaths since July 2017.To date, there is no specific treatment available for YF.Recently published papers describing in vitro and animal models suggest a potential effect of antiviral drugs (approved for the treatment Avena Sativa of

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Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach

Anti-angiogenic agents are biological drugs used for treatment of retinal neovascular degenerative diseases.In this study, we aimed at in-silico analysis of interaction of vascular endothelial growth factor A (VEGFA), the main mediator of angiogenesis, with binding domains of anti-angiogenic agents used for treatment of retinal diseases, such as ra

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